| 2017-09-02 15:00:002nd September 2017 |  Preston Grasshoppers 2 v Sale FC 2 | 29 - 21 | | Recap |
| 2017-09-09 15:00:009th September 2017 |  Sale FC 2 v Firwood Waterloo 2 | 7 - 21 | | Recap |
| 2017-09-16 15:00:4316th September 2017 |  Caldy 2 vs Sale FC 2 | 62 - 12 | | Recap |
| 2017-09-23 15:00:0023rd September 2017 |  Sale FC 2 v Sedgley Park 2 | L - W | | Recap |
| 2017-09-30 15:00:0030th September 2017 |  Sale FC 2 v Macclesfield 2 | 19 - 15 | | Recap |
| 2017-10-14 15:00:4414th October 2017 | Sale FC 2 v Sedgley Park 2 | 20 - 24 | | Recap |
| 2017-11-11 15:00:0011th November 2017 | Sedgley Park 2 v Sale FC 2 | 15:00:0015:00 | | Recap |
| 2017-11-18 15:00:0018th November 2017 | Sale FC 2 v Caldy 2 | 15:00:0015:00 | | Recap |
| 2017-12-02 15:00:002nd December 2017 |  Sale FC 2 v Fylde 2 | 15:00:0015:00 | | Recap |
| 2018-01-06 15:00:006th January 2018 | Sale FC 2 v Firwood Waterloo 2 | 15:00:0015:00 | | Recap |
| 2018-01-13 15:00:0013th January 2018 | Caldy 2 v Sale FC 2 | 15:00:0015:00 | | Recap |
| 2018-01-20 15:00:0020th January 2018 | Sale FC 2 v Sedgley Park 2 | 15:00:0015:00 | | Recap |
| 2018-01-27 15:00:0027th January 2018 | Sale FC 2 v Macclesfield 2 | 15:00:0015:00 | | Recap |
| 2018-02-03 15:00:003rd February 2018 | Fylde 2 v Sale FC 2 | 15:00:0015:00 | | Recap |
| 2018-02-17 15:00:0017th February 2018 |  Sale FC 2 v Chester 2 | 15:00:0015:00 | | Recap |
| 2018-02-24 15:00:0024th February 2018 | Firwood Waterloo 2 v Sale FC 2 | 15:00:0015:00 | | Recap |
| 2018-03-03 15:00:003rd March 2018 | Sale FC 2 v Preston 2 | 15:00:0015:00 | | Recap |
| 2018-03-10 15:00:0010th March 2018 | Sedgley Park 2 v Sale FC 2 | 15:00:0015:00 | | Recap |
| 2018-03-24 15:00:0024th March 2018 | Sale FC 2 v Caldy 2 | 15:00:0015:00 | | Recap |
| 2018-04-07 15:00:007th April 2018 | Chester 2 v Sale FC 2 | 15:00:0015:00 | | Recap |
| 2018-04-21 15:00:0021st April 2018 | Macclesfield 2 v Sale FC 2 | 15:00:0015:00 | | Recap |
